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» A New Similarity Measure among Protein Sequences
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BMCBI
2006
121views more  BMCBI 2006»
13 years 9 months ago
Robust computational reconstitution - a new method for the comparative analysis of gene expression in tissues and isolated cell
Background: Biological tissues consist of various cell types that differentially contribute to physiological and pathophysiological processes. Determining and analyzing cell type-...
Martin Hoffmann, Dirk Pohlers, Dirk Koczan, Hans-J...
BMCBI
2006
108views more  BMCBI 2006»
13 years 9 months ago
An improved map of conserved regulatory sites for Saccharomyces cerevisiae
Background: The regulatory map of a genome consists of the binding sites for proteins that determine the transcription of nearby genes. An initial regulatory map for S. cerevisiae...
Kenzie D. MacIsaac, Ting Wang, D. Benjamin Gordon,...
BMCBI
2005
97views more  BMCBI 2005»
13 years 9 months ago
Phylogenetic reconstruction of ancestral character states for gene expression and mRNA splicing data
Background: As genomes evolve after speciation, gene content, coding sequence, gene expression, and splicing all diverge with time from ancestors with close relatives. A minimum e...
Roald Rossnes, Ingvar Eidhammer, David A. Liberles
ICWE
2010
Springer
14 years 2 months ago
Combining Schema and Level-Based Matching for Web Service Discovery
Due to the availability of huge number of Web services (WSs), finding an appropriate WS according to the requirement of a service consumer is still a challenge. In this paper, we ...
Alsayed Algergawy, Richi Nayak, Norbert Siegmund, ...
ALGORITHMICA
1999
84views more  ALGORITHMICA 1999»
13 years 9 months ago
Computational Approaches to Drug Design
Abstract. The rational approach to pharmaceutical drug design begins with an investigation of the relationship between chemical structure and biological activity. Information gaine...
Paul W. Finn, Lydia E. Kavraki