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BMCBI
2006
165views more  BMCBI 2006»
13 years 7 months ago
Validation and functional annotation of expression-based clusters based on gene ontology
Background: The biological interpretation of large-scale gene expression data is one of the paramount challenges in current bioinformatics. In particular, placing the results in t...
Ralf Steuer, Peter Humburg, Joachim Selbig
RECOMB
2002
Springer
14 years 7 months ago
Discovering local structure in gene expression data: the order-preserving submatrix problem
This paper concerns the discovery of patterns in gene expression matrices, in which each element gives the expression level of a given gene in a given experiment. Most existing me...
Amir Ben-Dor, Benny Chor, Richard M. Karp, Zohar Y...
BMCBI
2005
122views more  BMCBI 2005»
13 years 7 months ago
GenClust: A genetic algorithm for clustering gene expression data
Background: Clustering is a key step in the analysis of gene expression data, and in fact, many classical clustering algorithms are used, or more innovative ones have been designe...
Vito Di Gesù, Raffaele Giancarlo, Giosu&egr...
BIOINFORMATICS
2007
137views more  BIOINFORMATICS 2007»
13 years 7 months ago
Annotation-based distance measures for patient subgroup discovery in clinical microarray studies
: Background Clustering algorithms are widely used in the analysis of microarray data. In clinical studies, they are often applied to find groups of co-regulated genes. Clustering...
Claudio Lottaz, Joern Toedling, Rainer Spang
BICOB
2009
Springer
13 years 5 months ago
A Biclustering Method to Discover Co-regulated Genes Using Diverse Gene Expression Datasets
We propose a two-step biclustering approach to mine co-regulation patterns of a given reference gene to discover other genes that function in a common biological process. Currently...
Doruk Bozdag, Jeffrey D. Parvin, Ümit V. &Cce...