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BMCBI
2005
141views more  BMCBI 2005»
13 years 8 months ago
Construction and validation of the APOCHIP, a spotted oligo-microarray for the study of beta-cell apoptosis
Background: Type 1 diabetes mellitus (T1DM) is a autoimmune disease caused by a long-term negative balance between immune-mediated beta-cell damage and beta-cell repair/regenerati...
Nils E. Magnusson, Alessandra K. Cardozo, Mogens K...
BMCBI
2010
154views more  BMCBI 2010»
13 years 8 months ago
Candidate gene prioritization by network analysis of differential expression using machine learning approaches
Background: Discovering novel disease genes is still challenging for diseases for which no prior knowledge - such as known disease genes or disease-related pathways - is available...
Daniela Nitsch, Joana P. Gonçalves, Fabian ...
DC
2010
13 years 5 months ago
Rambo: a robust, reconfigurable atomic memory service for dynamic networks
In this paper, we present RAMBO, an algorithm for emulating a read/write distributed shared memory in a dynamic, rapidly changing environment. RAMBO provides a highly reliable, hi...
Seth Gilbert, Nancy A. Lynch, Alexander A. Shvarts...
BMCBI
2008
96views more  BMCBI 2008»
13 years 8 months ago
Use of normalization methods for analysis of microarrays containing a high degree of gene effects
Background: High-throughput microarrays are widely used to study gene expression across tissues and developmental stages. Analysis of gene expression data is challenging in these ...
Terri T. Ni, William J. Lemon, Yu Shyr, Tao P. Zho...
BMCBI
2008
106views more  BMCBI 2008»
13 years 8 months ago
Comparison of normalisation methods for surface-enhanced laser desorption and ionisation (SELDI) time-of-flight (TOF) mass spect
Background: Mass spectrometry for biological data analysis is an active field of research, providing an efficient way of high-throughput proteome screening. A popular variant of m...
Wouter Meuleman, Judith Y. M. N. Engwegen, Marie-C...