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» A Physicochemical Model for Analyzing DNA Sequences
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BMCBI
2008
130views more  BMCBI 2008»
13 years 6 months ago
An enhanced partial order curve comparison algorithm and its application to analyzing protein folding trajectories
Background: Understanding how proteins fold is essential to our quest in discovering how life works at the molecular level. Current computation power enables researchers to produc...
Hong Sun, Hakan Ferhatosmanoglu, Motonori Ota, Yus...
ISMB
1998
13 years 8 months ago
Computational Applications of DNA Structural Scales
We study from a computational standpoint several different physicalscales associatedwith structural features of DNA sequences, including dinucleotide scales such as base stacking ...
Pierre Baldi, Søren Brunak, Yves Chauvin, A...
BMCBI
2008
132views more  BMCBI 2008»
13 years 6 months ago
The Average Mutual Information Profile as a Genomic Signature
Background: Occult organizational structures in DNA sequences may hold the key to understanding functional and evolutionary aspects of the DNA molecule. Such structures can also p...
Mark Bauer, Sheldon M. Schuster, Khalid Sayood
RECOMB
2010
Springer
14 years 1 months ago
Genomic DNA k-mer Spectra: Models and Modalities
Background: The empirical frequencies of DNA k-mers in whole genome sequences provide an interesting perspective on genomic complexity, and the availability of large segments of g...
Benny Chor, David Horn, Nick Goldman, Yaron Levy, ...
BMCBI
2010
121views more  BMCBI 2010»
13 years 4 months ago
Computing DNA duplex instability profiles efficiently with a two-state model: trends of promoters and binding sites
Background: DNA instability profiles have been used recently for predicting the transcriptional start site and the location of core promoters, and to gain insight into promoter ac...
Miriam R. Kantorovitz, Zoi Rapti, Vladimir Gelev, ...