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BMCBI
2008
131views more  BMCBI 2008»
15 years 4 months ago
K-OPLS package: Kernel-based orthogonal projections to latent structures for prediction and interpretation in feature space
Background: Kernel-based classification and regression methods have been successfully applied to modelling a wide variety of biological data. The Kernel-based Orthogonal Projectio...
Max Bylesjö, Mattias Rantalainen, Jeremy K. N...
BMCBI
2008
138views more  BMCBI 2008»
15 years 4 months ago
Inference of haplotypic phase and missing genotypes in polyploid organisms and variable copy number genomic regions
Background: The power of haplotype-based methods for association studies, identification of regions under selection, and ancestral inference, is well-established for diploid organ...
Shu-Yi Su, Jonathan White, David J. Balding, Lachl...
BMCBI
2008
117views more  BMCBI 2008»
15 years 4 months ago
CrossHybDetector: detection of cross-hybridization events in DNA microarray experiments
Background: DNA microarrays contain thousands of different probe sequences represented on their surface. These are designed in such a way that potential cross-hybridization reacti...
Paolo Uva, Emanuele de Rinaldis
BMCBI
2008
130views more  BMCBI 2008»
15 years 4 months ago
Structural descriptor database: a new tool for sequence-based functional site prediction
Background: The Structural Descriptor Database (SDDB) is a web-based tool that predicts the function of proteins and functional site positions based on the structural properties o...
Juliana S. Bernardes, Jorge H. Fernandez, Ana Tere...
BMCBI
2008
107views more  BMCBI 2008»
15 years 4 months ago
Probe-specific mixed-model approach to detect copy number differences using multiplex ligation-dependent probe amplification (ML
Background: MLPA method is a potentially useful semi-quantitative method to detect copy number alterations in targeted regions. In this paper, we propose a method for the normaliz...
Juan R. González, Josep L. Carrasco, Llu&ia...