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BMCBI
2005
147views more  BMCBI 2005»
15 years 4 months ago
Calibration of mass spectrometric peptide mass fingerprint data without specific external or internal calibrants
Background: Peptide Mass Fingerprinting (PMF) is a widely used mass spectrometry (MS) method of analysis of proteins and peptides. It relies on the comparison between experimental...
Witold E. Wolski, Maciej Lalowski, Peter Jungblut,...
BMCBI
2005
97views more  BMCBI 2005»
15 years 4 months ago
Comparative mapping of sequence-based and structure-based protein domains
Background: Protein domains have long been an ill-defined concept in biology. They are generally described as autonomous folding units with evolutionary and functional independenc...
Ya Zhang, John-Marc Chandonia, Chris H. Q. Ding, S...
BMCBI
2005
104views more  BMCBI 2005»
15 years 4 months ago
An integrated approach of immunogenomics and bioinformatics to identify new Tumor Associated Antigens (TAA) for mammary cancer i
Background: Neoplastic transformation is a multistep process in which distinct gene products of specific cell regulatory pathways are involved at each stage. Identification of ove...
Federica Cavallo, Annalisa Astolfi, Manuela Iezzi,...
BMCBI
2005
125views more  BMCBI 2005»
15 years 4 months ago
Query3d: a new method for high-throughput analysis of functional residues in protein structures
Background: The identification of local similarities between two protein structures can provide clues of a common function. Many different methods exist for searching for similar ...
Gabriele Ausiello, Allegra Via, Manuela Helmer-Cit...
BMCBI
2005
126views more  BMCBI 2005»
15 years 4 months ago
HomoMINT: an inferred human network based on orthology mapping of protein interactions discovered in model organisms
Background: The application of high throughput approaches to the identification of protein interactions has offered for the first time a glimpse of the global interactome of some ...
Maria Persico, Arnaud Ceol, Caius Gavrila, Robert ...