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BMCBI
2006
166views more  BMCBI 2006»
13 years 7 months ago
SEQOPTICS: a protein sequence clustering system
Background: Protein sequence clustering has been widely used as a part of the analysis of protein structure and function. In most cases single linkage or graph-based clustering al...
Yonghui Chen, Kevin D. Reilly, Alan P. Sprague, Zh...
BMCBI
2010
123views more  BMCBI 2010»
13 years 7 months ago
An improved classification of G-protein-coupled receptors using sequence-derived features
Background: G-protein-coupled receptors (GPCRs) play a key role in diverse physiological processes and are the targets of almost two-thirds of the marketed drugs. The 3 D structur...
Zhen-Ling Peng, Jian-Yi Yang, Xin Chen
TCBB
2011
13 years 2 months ago
Data Mining on DNA Sequences of Hepatitis B Virus
: Extraction of meaningful information from large experimental datasets is a key element of bioinformatics research. One of the challenges is to identify genomic markers in Hepatit...
Kwong-Sak Leung, Kin-Hong Lee, Jin Feng Wang, Eddi...
CANDC
2004
ACM
13 years 7 months ago
The iProClass integrated database for protein functional analysis
Increasingly, scientists have begun to tackle gene functions and other complex regulatory processes by studying organisms at the global scales for various levels of biological org...
Cathy H. Wu, Hongzhan Huang, Anastasia N. Nikolska...
ISMB
2001
13 years 9 months ago
Using mixtures of common ancestors for estimating the probabilities of discrete events in biological sequences
Accurately estimating probabilities from observations is important for probabilistic-based approaches to problems in computational biology. In this paper we present a biologically...
Eleazar Eskin, William Noble Grundy, Yoram Singer