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» A Quality Measure for Distributed Clustering
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ALMOB
2008
85views more  ALMOB 2008»
13 years 7 months ago
Noisy: Identification of problematic columns in multiple sequence alignments
Motivation: Sequence-based methods for phylogenetic reconstruction from (nucleic acid) sequence data are notoriously plagued by two effects: homoplasies and alignment errors. Larg...
Andreas W. M. Dress, Christoph Flamm, Guido Fritzs...
BMCBI
2010
136views more  BMCBI 2010»
13 years 7 months ago
An integrated Bayesian analysis of LOH and copy number data
Background: Cancer and other disorders are due to genomic lesions. SNP-microarrays are able to measure simultaneously both genotype and copy number (CN) at several Single Nucleoti...
Paola M. V. Rancoita, Marcus Hutter, Francesco Ber...
BMCBI
2008
95views more  BMCBI 2008»
13 years 7 months ago
Unsupervised reduction of random noise in complex data by a row-specific, sorted principal component-guided method
Background: Large biological data sets, such as expression profiles, benefit from reduction of random noise. Principal component (PC) analysis has been used for this purpose, but ...
Joseph W. Foley, Fumiaki Katagiri
CN
2008
127views more  CN 2008»
13 years 7 months ago
Decentralized detection of global threshold crossings using aggregation trees
The timely detection that a monitored variable has crossed a given threshold is a fundamental requirement for many network management applications. A challenge is the detection of ...
Fetahi Wuhib, Mads Dam, Rolf Stadler
BMCBI
2006
138views more  BMCBI 2006»
13 years 7 months ago
Approximation properties of haplotype tagging
Background: Single nucleotide polymorphisms (SNPs) are locations at which the genomic sequences of population members differ. Since these differences are known to follow patterns,...
Staal A. Vinterbo, Stephan Dreiseitl, Lucila Ohno-...