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BMCBI
2010
123views more  BMCBI 2010»
13 years 7 months ago
Prediction of breast cancer prognosis using gene set statistics provides signature stability and biological context
Background: Different microarray studies have compiled gene lists for predicting outcomes of a range of treatments and diseases. These have produced gene lists that have little ov...
Gad Abraham, Adam Kowalczyk, Sherene Loi, Izhak Ha...
BMCBI
2010
114views more  BMCBI 2010»
13 years 7 months ago
An integrative modular approach to systematically predict gene-phenotype associations
Background: Complex human diseases are often caused by multiple mutations, each of which contributes only a minor effect to the disease phenotype. To study the basis for these com...
Michael R. Mehan, Juan Nunez-Iglesias, Chao Dai, M...
BIBE
2007
IEEE
162views Bioinformatics» more  BIBE 2007»
14 years 2 months ago
An Investigation into the Feasibility of Detecting Microscopic Disease Using Machine Learning
— The prognosis for many cancers could be improved dramatically if they could be detected while still at the microscopic disease stage. We are investigating the possibility of de...
Mary Qu Yang, Jack Y. Yang
ISMB
2000
13 years 9 months ago
A Probabilistic Learning Approach to Whole-Genome Operon Prediction
We present a computational approach to predicting operons in the genomes of prokaryotic organisms. Our approach uses machine learning methods to induce predictive models for this ...
Mark Craven, David Page, Jude W. Shavlik, Joseph B...
BMCBI
2010
132views more  BMCBI 2010»
13 years 7 months ago
Error margin analysis for feature gene extraction
Background: Feature gene extraction is a fundamental issue in microarray-based biomarker discovery. It is normally treated as an optimization problem of finding the best predictiv...
Chi Kin Chow, Hai Long Zhu, Jessica Lacy, Winston ...