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BMCBI
2008
114views more  BMCBI 2008»
13 years 6 months ago
TiGER: A database for tissue-specific gene expression and regulation
Background: Understanding how genes are expressed and regulated in different tissues is a fundamental and challenging question. However, most of currently available biological dat...
Xiong Liu, Xueping Yu, Donald J. Zack, Heng Zhu, J...
TCBB
2010
91views more  TCBB 2010»
13 years 1 months ago
SCS: Signal, Context, and Structure Features for Genome-Wide Human Promoter Recognition
This paper integrates the signal, context and structure features for genome-wide promoter recognition, which is critical in many DNA sequence analysis tasks. First, CpG islands ar...
Jia Zeng, Xiaoyu Zhao, Xiao-Qin Cao, Hong Yan
BMCBI
2010
177views more  BMCBI 2010»
13 years 6 months ago
Modular composition predicts kinase/substrate interactions
Background: Phosphorylation events direct the flow of signals and metabolites along cellular protein networks. Current annotations of kinase-substrate binding events are far from ...
Yichuan Liu, Aydin Tozeren
BMCBI
2006
98views more  BMCBI 2006»
13 years 6 months ago
Quantitative comparison of EST libraries requires compensation for systematic biases in cDNA generation
Background: Publicly accessible EST libraries contain valuable information that can be utilized for studies of tissue-specific gene expression and processing of individual genes. ...
Donglin Liu, Joel H. Graber
BMCBI
2008
121views more  BMCBI 2008»
13 years 6 months ago
ReAlignerV: Web-based genomic alignment tool with high specificity and robustness estimated by species-specific insertion sequen
Background: Detecting conserved noncoding sequences (CNSs) across species highlights the functional elements. Alignment procedures combined with computational prediction of transc...
Hisakazu Iwama, Yukio Hori, Kensuke Matsumoto, Koj...