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BMCBI
2005
130views more  BMCBI 2005»
13 years 7 months ago
Some statistical properties of regulatory DNA sequences, and their use in predicting regulatory regions in the Drosophila genome
Background: This paper addresses the problem of recognising DNA cis-regulatory modules which are located far from genes. Experimental procedures for this are slow and costly, and ...
Irina I. Abnizova, Rene te Boekhorst, Klaudia Walt...
IJBRA
2006
61views more  IJBRA 2006»
13 years 7 months ago
Finding functional promoter motifs by computational methods: a word of caution
: The standard practice in the analysis of promoters is to select promoter regions of convenient length. This may lead to false results when searching for Transcription Factor Bind...
Rajesh Chowdhary, Limsoon Wong, Vladimir B. Bajic
BMCBI
2005
169views more  BMCBI 2005»
13 years 7 months ago
MAPPER: a search engine for the computational identification of putative transcription factor binding sites in multiple genomes
Background: Cis-regulatory modules are combinations of regulatory elements occurring in close proximity to each other that control the spatial and temporal expression of genes. Th...
Voichita D. Marinescu, Isaac S. Kohane, Alberto Ri...
BIOINFORMATICS
2012
11 years 9 months ago
Epigenetic priors for identifying active transcription factor binding sites
Motivation Accurate knowledge of the genome-wide binding of transcription factors in a particular cell type or under a particular condition is necessary for understanding transcri...
Gabriel Cuellar-Partida, Fabian A. Buske, Robert C...
BMCBI
2010
108views more  BMCBI 2010»
13 years 7 months ago
An intuitionistic approach to scoring DNA sequences against transcription factor binding site motifs
Background: Transcription factors (TFs) control transcription by binding to specific regions of DNA called transcription factor binding sites (TFBSs). The identification of TFBSs ...
Fernando Garcia-Alcalde, Armando Blanco, Adrian J....