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BMCBI
2010
154views more  BMCBI 2010»
13 years 7 months ago
An eScience-Bayes strategy for analyzing omics data
Background: The omics fields promise to revolutionize our understanding of biology and biomedicine. However, their potential is compromised by the challenge to analyze the huge da...
Martin Eklund, Ola Spjuth, Jarl E. S. Wikberg
IFIP
2004
Springer
14 years 1 months ago
Efficient Algorithms for Handling Molecular Weighted Sequences
Abstract In this paper we introduce the Weighted Suffix Tree, an efficient data structure for computing string regularities in weighted sequences of molecular data. Molecular Wei...
Costas S. Iliopoulos, Christos Makris, Yannis Pana...
ISMB
1998
13 years 9 months ago
Advanced Query Mechanisms for Biological Databases
Existing query interfaces for biological databases are either based on fixed forms or textual query languages. Users of a fixed form-based query interface are limited to performin...
I-Min A. Chen, Anthony Kosky, Victor M. Markowitz,...
BMCBI
2008
149views more  BMCBI 2008»
13 years 7 months ago
Evolution of biological sequences implies an extreme value distribution of type I for both global and local pairwise alignment s
Background: Confidence in pairwise alignments of biological sequences, obtained by various methods such as Blast or Smith-Waterman, is critical for automatic analyses of genomic d...
Olivier Bastien, Eric Maréchal
AB
2007
Springer
13 years 11 months ago
Efficient Haplotype Inference with Pseudo-boolean Optimization
Abstract. Haplotype inference from genotype data is a key computational problem in bioinformatics, since retrieving directly haplotype information from DNA samples is not feasible ...
Ana Graça, João Marques-Silva, In&ec...