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BMCBI
2010
121views more  BMCBI 2010»
13 years 6 months ago
A Markov blanket-based method for detecting causal SNPs in GWAS
Background: Detecting epistatic interactions associated with complex and common diseases can help to improve prevention, diagnosis and treatment of these diseases. With the develo...
Bing Han, Meeyoung Park, Xue-wen Chen
GECCO
2009
Springer
115views Optimization» more  GECCO 2009»
13 years 11 months ago
Rapid prototyping using evolutionary approaches: part 2
In this paper we extend the work done in [5], where authors have proposed a evolutionary multi-objective approach to Rapid Prototyping (RP), to decipher optimal build orientation ...
Nikhil Padhye, Subodh Kalia
CIKM
2006
Springer
13 years 10 months ago
Describing differences between databases
We study the novel problem of efficiently computing the update distance for a pair of relational databases. In analogy to the edit distance of strings, we define the update distan...
Heiko Müller, Johann Christoph Freytag, Ulf L...
BMCBI
2008
186views more  BMCBI 2008»
13 years 6 months ago
Variable selection for large p small n regression models with incomplete data: Mapping QTL with epistases
Background: Identifying quantitative trait loci (QTL) for both additive and epistatic effects raises the statistical issue of selecting variables from a large number of candidates...
Min Zhang, Dabao Zhang, Martin T. Wells
BMCBI
2006
113views more  BMCBI 2006»
13 years 6 months ago
QualitySNP: a pipeline for detecting single nucleotide polymorphisms and insertions/deletions in EST data from diploid and polyp
Background: Single nucleotide polymorphisms (SNPs) are important tools in studying complex genetic traits and genome evolution. Computational strategies for SNP discovery make use...
Jifeng Tang, Ben Vosman, Roeland E. Voorrips, C. G...