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BMCBI
2010
172views more  BMCBI 2010»
13 years 7 months ago
Comparison of evolutionary algorithms in gene regulatory network model inference
Background: The evolution of high throughput technologies that measure gene expression levels has created a data base for inferring GRNs (a process also known as reverse engineeri...
Alina Sîrbu, Heather J. Ruskin, Martin Crane
BMCBI
2010
82views more  BMCBI 2010»
13 years 7 months ago
Predicting the network of substrate-enzyme-product triads by combining compound similarity and functional domain composition
Background: Metabolic pathway is a highly regulated network consisting of many metabolic reactions involving substrates, enzymes, and products, where substrates can be transformed...
Lei Chen, Kai-Yan Feng, Yu-Dong Cai, Kuo-Chen Chou...
BMCBI
2008
141views more  BMCBI 2008»
13 years 7 months ago
EzArray: A web-based highly automated Affymetrix expression array data management and analysis system
Background: Though microarray experiments are very popular in life science research, managing and analyzing microarray data are still challenging tasks for many biologists. Most m...
Yuerong Zhu, Yuelin Zhu, Wei Xu
BMCBI
2008
107views more  BMCBI 2008»
13 years 7 months ago
Multi-agent systems in epidemiology: a first step for computational biology in the study of vector-borne disease transmission
Background: Computational biology is often associated with genetic or genomic studies only. However, thanks to the increase of computational resources, computational models are ap...
Benjamin Roche, Jean-François Guégan...
BMCBI
2008
132views more  BMCBI 2008»
13 years 7 months ago
The Average Mutual Information Profile as a Genomic Signature
Background: Occult organizational structures in DNA sequences may hold the key to understanding functional and evolutionary aspects of the DNA molecule. Such structures can also p...
Mark Bauer, Sheldon M. Schuster, Khalid Sayood