Background: New systems biology studies require researchers to understand how interplay among myriads of biomolecular entities is orchestrated in order to achieve high-level cellu...
Tianxiao Huan, Andrey Y. Sivachenko, Scott H. Harr...
One of the issues in software evolution is debugging. Debugging large and complex software systems evolved requires a lot of effort since it is very difficult to localize and ide...
Background: The incorporation of annotated sequence information from multiple related species in commonly used databases (Ensembl, Flybase, Saccharomyces Genome Database, Wormbase...
Steven N. Steinway, Ruth Dannenfelser, Christopher...
Designing complex multi-tier applications that must meet strict performance requirements is a challenging software engineering problem. Ideally, the application architect could de...
Despite Java’s automatic reclamation of memory, memory leaks remain an important problem. For example, we frequently encounter memory leaks that cause production servers to crash...