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BMCBI
2008
13 years 7 months ago
2008
Background: Designing small-molecule kinase inhibitors with desirable selectivity profiles is a major challenge in drug discovery. A high-throughput screen for inhibitors of a giv...
BMCBI
2006
13 years 7 months ago
2006
Background: Microarrays permit biologists to simultaneously measure the mRNA abundance of thousands of genes. An important issue facing investigators planning microarray experimen...
IJSEKE
2006
13 years 7 months ago
2006
pecific models increase the level of abstraction used to develop large-scale component-based systems. Model-driven development (MDD) approaches (e.g., ModelIntegrated Computing and...
SYNTHESE
2008
13 years 7 months ago
2008
The paper is concerned with how neo-Lockean accounts of personal identity should respond to the challenge of animalist accounts. Neo-Lockean accounts that hold that persons can cha...
JAIR
2007
13 years 7 months ago
2007
One of the biggest challenges in the development and deployment of spoken dialogue systems is the design of the spoken language generation module. This challenge arises from the n...