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» A computational view of population genetics
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ISBI
2008
IEEE
14 years 9 months ago
Comparison of fractional and geodesic anisotropy in diffusion tensor images of 90 monozygotic and dizygotic twins
We used diffusion tensor magnetic resonance imaging (DTI) to reveal the extent of genetic effects on brain fiber microstructure, based on tensor-derived measures, in 22 pairs of m...
Agatha D. Lee, Natasha Lepore, Marina Barysheva, Y...
RECOMB
2002
Springer
14 years 9 months ago
Inferring Piecewise Ancestral History from Haploid Sequences
There has been considerable recent interest in the use of haplotype structure to aid in the design and analysis of case-control association studies searching for genetic predictors...
Russell Schwartz, Andrew G. Clark, Sorin Istrail
BMCBI
2010
148views more  BMCBI 2010»
13 years 8 months ago
Calling SNPs without a reference sequence
Background: The most common application for the next-generation sequencing technologies is resequencing, where short reads from the genome of an individual are aligned to a refere...
Aakrosh Ratan, Yu Zhang, Vanessa M. Hayes, Stephan...
BMCBI
2010
134views more  BMCBI 2010»
13 years 8 months ago
R-Gada: a fast and flexible pipeline for copy number analysis in association studies
Background: Genome-wide association studies (GWAS) using Copy Number Variation (CNV) are becoming a central focus of genetic research. CNVs have successfully provided target genom...
Roger Pique-Regi, Alejandro Cáceres, Juan R...
EC
2006
163views ECommerce» more  EC 2006»
13 years 8 months ago
An Extension of Geiringer's Theorem for a Wide Class of Evolutionary Search Algorithms
The frequency with which various elements of the search space of a given evolutionary algorithm are sampled is affected by the family of recombination (reproduction) operators. Th...
Boris Mitavskiy, Jonathan E. Rowe