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» A cross-comparison of a large dataset of genes
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BMCBI
2010
193views more  BMCBI 2010»
13 years 2 months ago
Mayday - integrative analytics for expression data
Background: DNA Microarrays have become the standard method for large scale analyses of gene expression and epigenomics. The increasing complexity and inherent noisiness of the ge...
Florian Battke, Stephan Symons, Kay Nieselt
BMCBI
2006
75views more  BMCBI 2006»
13 years 7 months ago
Improving the specificity of high-throughput ortholog prediction
Background: Orthologs (genes that have diverged after a speciation event) tend to have similar function, and so their prediction has become an important component of comparative g...
Debra L. Fulton, Yvonne Y. Li, Matthew R. Laird, B...
VLDB
2007
ACM
128views Database» more  VLDB 2007»
14 years 7 months ago
Periscope/SQ: Interactive Exploration of Biological Sequence Databases
Life science laboratories today have to rely on procedural techniques to store and manage large sequence datasets. Procedural techniques are cumbersome to use and are often very i...
Sandeep Tata, Willis Lang, Jignesh M. Patel
BMCBI
2010
189views more  BMCBI 2010»
13 years 5 months ago
solQTL: a tool for QTL analysis, visualization and linking to genomes at SGN database
Background: A common approach to understanding the genetic basis of complex traits is through identification of associated quantitative trait loci (QTL). Fine mapping QTLs require...
Isaak Y. Tecle, Naama Menda, Robert M. Buels, Esth...
BMCBI
2010
120views more  BMCBI 2010»
13 years 7 months ago
Modeling expression quantitative trait loci in data combining ethnic populations
Background: Combining data from different ethnic populations in a study can increase efficacy of methods designed to identify expression quantitative trait loci (eQTL) compared to...
Ching-Lin Hsiao, Ie-Bin Lian, Ai-Ru Hsieh, Cathy S...