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» A cross-comparison of a large dataset of genes
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BMCBI
2006
130views more  BMCBI 2006»
13 years 7 months ago
An accurate and interpretable model for siRNA efficacy prediction
Background: The use of exogenous small interfering RNAs (siRNAs) for gene silencing has quickly become a widespread molecular tool providing a powerful means for gene functional s...
Jean-Philippe Vert, Nicolas Foveau, Christian Laja...
BMCBI
2010
96views more  BMCBI 2010»
13 years 7 months ago
ChIPpeakAnno: a Bioconductor package to annotate ChIP-seq and ChIP-chip data
Background: Chromatin immunoprecipitation (ChIP) followed by high-throughput sequencing (ChIP-seq) or ChIP followed by genome tiling array analysis (ChIP-chip) have become standar...
Lihua J. Zhu, Claude Gazin, Nathan D. Lawson, Herv...
BMCBI
2010
151views more  BMCBI 2010»
13 years 7 months ago
Data reduction for spectral clustering to analyze high throughput flow cytometry data
Background: Recent biological discoveries have shown that clustering large datasets is essential for better understanding biology in many areas. Spectral clustering in particular ...
Habil Zare, Parisa Shooshtari, Arvind Gupta, Ryan ...
SP
2008
IEEE
122views Security Privacy» more  SP 2008»
13 years 7 months ago
Large-scale phylogenetic analysis on current HPC architectures
Abstract. Phylogenetic inference is considered a grand challenge in Bioinformatics due to its immense computational requirements. The increasing popularity and availability of larg...
Michael Ott, Jaroslaw Zola, Srinivas Aluru, Andrew...
BMCBI
2006
98views more  BMCBI 2006»
13 years 7 months ago
JLIN: A java based linkage disequilibrium plotter
Background: A great deal of effort and expense are being expended internationally in attempts to detect genetic polymorphisms contributing to susceptibility to complex human disea...
Kim W. Carter, Pamela A. McCaskie, Lyle J. Palmer