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» A factor analysis model for functional genomics
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BMCBI
2006
95views more  BMCBI 2006»
13 years 8 months ago
XcisClique: analysis of regulatory bicliques
Background: Modeling of cis-elements or regulatory motifs in promoter (upstream) regions of genes is a challenging computational problem. In this work, set of regulatory motifs si...
Amrita Pati, Cecilia Vasquez-Robinet, Lenwood S. H...
IMR
2005
Springer
14 years 1 months ago
A Computational Framework for Generating Sizing Function in Assembly Meshing
This paper proposes a framework for generating sizing function in meshing assemblies. Size control is crucial in obtaining a high-quality mesh with a reduced number of elements, w...
William Roshan Quadros, Ved Vyas, Michael L. Brewe...
BMCBI
2010
135views more  BMCBI 2010»
13 years 8 months ago
Efficient genome-scale phylogenetic analysis under the duplication-loss and deep coalescence cost models
Background: Genomic data provide a wealth of new information for phylogenetic analysis. Yet making use of this data requires phylogenetic methods that can efficiently analyze extr...
Mukul S. Bansal, J. Gordon Burleigh, Oliver Eulens...
BMCBI
2010
104views more  BMCBI 2010»
13 years 8 months ago
Bidirectional best hit r-window gene clusters
Background: Conserved gene clusters are groups of genes that are located close to one another in the genomes of several species. They tend to code for proteins that have a functio...
Melvin Zhang, Hon Wai Leong
GECCO
2008
Springer
174views Optimization» more  GECCO 2008»
13 years 9 months ago
Mask functions for the symbolic modeling of epistasis using genetic programming
The study of common, complex multifactorial diseases in genetic epidemiology is complicated by nonlinearity in the genotype-to-phenotype mapping relationship that is due, in part,...
Ryan J. Urbanowicz, Nate Barney, Bill C. White, Ja...