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BMCBI
2008
158views more  BMCBI 2008»
13 years 9 months ago
Discovering gene annotations in biomedical text databases
Currently, most of the discovered biological and biomedical knowledge is available as textual data in scientific papers. And, locating and curating information about a genomic enti...
Ali Cakmak, Gultekin Özsoyoglu
BMCBI
2008
124views more  BMCBI 2008»
13 years 9 months ago
A probe-treatment-reference (PTR) model for the analysis of oligonucleotide expression microarrays
Background: Microarray pre-processing usually consists of normalization and summarization. Normalization aims to remove non-biological variations across different arrays. The norm...
Huanying Ge, Chao Cheng, Lei M. Li
BMCBI
2008
159views more  BMCBI 2008»
13 years 9 months ago
Estimation and testing for the effect of a genetic pathway on a disease outcome using logistic kernel machine regression via log
Background: Growing interest on biological pathways has called for new statistical methods for modeling and testing a genetic pathway effect on a health outcome. The fact that gen...
Dawei Liu, Debashis Ghosh, Xihong Lin
BMCBI
2008
129views more  BMCBI 2008»
13 years 9 months ago
Gene set enrichment analysis for non-monotone association and multiple experimental categories
Background: Recently, microarray data analyses using functional pathway information, e.g., gene set enrichment analysis (GSEA) and significance analysis of function and expression...
Rongheng Lin, Shuangshuang Dai, Richard D. Irwin, ...
BMCBI
2008
124views more  BMCBI 2008»
13 years 9 months ago
Ontology-based, Tissue MicroArray oriented, image centered tissue bank
Background: Tissue MicroArray technique is becoming increasingly important in pathology for the validation of experimental data from transcriptomic analysis. This approach produce...
Federica Viti, Ivan Merelli, Andrea Caprera, Barba...
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