Reverse-engineering of gene networks using linear models often results in an underdetermined system because of excessive unknown parameters. In addition, the practical utility of ...
Abstract. This paper presents a method for regulatory network reconstruction from experimental data. We propose a mathematical model for regulatory interactions, based on the work ...
: Array-based analysis of chromatin immunoprecipitation data (ChIP-chip) is a powerful technique for identifying DNA target regions of individual transcription factors. Here, we pr...
Michael Seifert, Jens Keilwagen, Marc Strickert, I...
Motivation: Cell-cycle regulated gene prediction using microarray time-course measurements of the mRNA expression levels of genes has been used by several researchers. The popular...
Background: High-density short oligonucleotide microarrays are a primary research tool for assessing global gene expression. Background noise on microarrays comprises a significan...