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» A framework for protein and membrane interactions
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SC
2005
ACM
14 years 18 days ago
SPICE: Simulated Pore Interactive Computing Environment
— SPICE aims to understand the vital process of translocation of biomolecules across protein pores by computing the free energy profile of the translocating biomolecule along th...
Shantenu Jha, Peter V. Coveney, Matt J. Harvey
JCB
2000
146views more  JCB 2000»
13 years 6 months ago
Bayesian Segmentation of Protein Secondary Structure
We present a novel method for predicting the secondary structure of a protein from its amino acid sequence. Most existing methods predict each position in turn based on a local wi...
Scott C. Schmidler, Jun S. Liu, Douglas L. Brutlag
BMCBI
2010
147views more  BMCBI 2010»
13 years 7 months ago
Learning biological network using mutual information and conditional independence
Background: Biological networks offer us a new way to investigate the interactions among different components and address the biological system as a whole. In this paper, a revers...
Dong-Chul Kim, Xiaoyu Wang, Chin-Rang Yang, Jean G...
CSB
2003
IEEE
153views Bioinformatics» more  CSB 2003»
14 years 10 days ago
Combining Microarrays and Biological Knowledge for Estimating Gene Networks via Bayesian Networks
We propose a statistical method for estimating a gene network based on Bayesian networks from microarray gene expression data together with biological knowledge including protein-...
Seiya Imoto, Tomoyuki Higuchi, Takao Goto, Kousuke...
BMCBI
2010
135views more  BMCBI 2010»
13 years 7 months ago
Lists2Networks: Integrated analysis of gene/protein lists
Background: Systems biologists are faced with the difficultly of analyzing results from large-scale studies that profile the activity of many genes, RNAs and proteins, applied in ...
Alexander Lachmann, Avi Ma'ayan