Background: The Significance Analysis of Microarrays (SAM) is a popular method for detecting significantly expressed genes and controlling the false discovery rate (FDR). Recently...
Many bioinformatics problems can implicitly depend on estimating large-scale covariance matrix. The traditional approaches tend to give rise to high variance and low accuracy esti...
Extracting dense sub-components from graphs efficiently is an important objective in a wide range of application domains ranging from social network analysis to biological network...
Nan Wang, Srinivasan Parthasarathy, Kian-Lee Tan, ...
Non-negative matrix factorization (NMF) has become a standard tool in data mining, information retrieval, and signal processing. It is used to factorize a non-negative data matrix ...
C. Thurau, K. Kersting, M. Wahabzada, and C. Bauck...
Background: Cis-regulatory modules are combinations of regulatory elements occurring in close proximity to each other that control the spatial and temporal expression of genes. Th...
Voichita D. Marinescu, Isaac S. Kohane, Alberto Ri...