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RECOMB
2003
Springer
14 years 7 months ago
Phylogenetically and spatially conserved word pairs associated with gene expression changes in yeasts
Background: Transcriptional regulation in eukaryotes often involves multiple transcription factors binding to the same transcription control region, and to understand the regulato...
Derek Y. Chiang, Alan M. Moses, Manolis Kamvysseli...
BMCBI
2008
128views more  BMCBI 2008»
13 years 7 months ago
Validation of an NSP-based (negative selection pattern) gene family identification strategy
Background: Gene family identification from ESTs can be a valuable resource for analysis of genome evolution but presents unique challenges in organisms for which the entire genom...
Ronald L. Frank, Cyriac Kandoth, Fikret Erç...
NAR
2002
138views more  NAR 2002»
13 years 7 months ago
The KEGG databases at GenomeNet
The Kyoto Encyclopedia of Genes and Genomes (KEGG) is the primary database resource of the Japanese GenomeNet service (http://www.genome.ad.jp/) for understanding higher order fun...
Minoru Kanehisa, Susumu Goto, Shuichi Kawashima, A...
BMCBI
2010
99views more  BMCBI 2010»
13 years 7 months ago
Different effects of the probe summarization algorithms PLIER and RMA on high-level analysis of Affymetrix exon arrays
Background: Alternative splicing is an important mechanism that increases protein diversity and functionality in higher eukaryotes. Affymetrix exon arrays are a commercialized pla...
Yi Qu, Fei He, Yuchen Chen
BMCBI
2008
90views more  BMCBI 2008»
13 years 7 months ago
Genome-scale study of the importance of binding site context for transcription factor binding and gene regulation
Background: The rate of mRNA transcription is controlled by transcription factors that bind to specific DNA motifs in promoter regions upstream of protein coding genes. Recent res...
Jakub Orzechowski Westholm, Feifei Xu, Hans Ronne,...