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BMCBI
2010
108views more  BMCBI 2010»
15 years 4 months ago
Predicting changes in protein thermostability brought about by single- or multi-site mutations
Background: An important aspect of protein design is the ability to predict changes in protein thermostability arising from single- or multi-site mutations. Protein thermostabilit...
Jian Tian, Ningfeng Wu, Xiaoyu Chu, Yunliu Fan
BMCBI
2006
85views more  BMCBI 2006»
15 years 3 months ago
Searching for interpretable rules for disease mutations: a simulated annealing bump hunting strategy
Background: Understanding how amino acid substitutions affect protein functions is critical for the study of proteins and their implications in diseases. Although methods have bee...
Rui Jiang, Hua Yang, Fengzhu Sun, Ting Chen
BMCBI
2005
201views more  BMCBI 2005»
15 years 3 months ago
A comparative study of discriminating human heart failure etiology using gene expression profiles
Background: Human heart failure is a complex disease that manifests from multiple genetic and environmental factors. Although ischemic and non-ischemic heart disease present clini...
Xiaohong Huang, Wei Pan, Suzanne Grindle, Xinqiang...
BMCBI
2004
135views more  BMCBI 2004»
15 years 3 months ago
Information assessment on predicting protein-protein interactions
Background: Identifying protein-protein interactions is fundamental for understanding the molecular machinery of the cell. Proteome-wide studies of protein-protein interactions ar...
Nan Lin, Baolin Wu, Ronald Jansen, Mark Gerstein, ...
CLEF
2009
Springer
15 years 1 months ago
ImageCLEF 2009 Medical Image Annotation Task: PCTs for Hierarchical Multi-Label Classification
In this paper, we describe an approach for the automatic medical image annotation task of the 2009 CLEF cross-language image retrieval campaign (ImageCLEF). This work is focused o...
Ivica Dimitrovski, Dragi Kocev, Suzana Loskovska, ...