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» A graphical model for predicting protein molecular function
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RECOMB
2002
Springer
14 years 8 months ago
A dimensionality reduction approach to modeling protein flexibility
Proteins are involved either directly or indirectly in all biological processes in living organisms. It is now widely accepted that conformational changes of proteins can critical...
Miguel L. Teodoro, George N. Phillips, Lydia E. Ka...
ISVC
2007
Springer
14 years 1 months ago
Integrative Geometric-Hashing Approaches to Binding Site Modeling and Ligand-Protein Interaction Prediction
Abstract. The function of a protein is dependent on whether and how it can interact with various ligands. Therefore, an accurate prediction of protein-ligand interactions is paramo...
Joanna Lipinski-Kruszka, Rahul Singh
RECOMB
2002
Springer
14 years 8 months ago
Combining pairwise sequence similarity and support vector machines for remote protein homology detection
One key element in understanding the molecular machinery of the cell is to understand the meaning, or function, of each protein encoded in the genome. A very successful means of i...
Li Liao, William Stafford Noble
BMCBI
2011
12 years 11 months ago
GPCR-SSFE: A comprehensive database of G-protein-coupled receptor template predictions and homology models
Background: G protein-coupled receptors (GPCRs) transduce a wide variety of extracellular signals to within the cell and therefore have a key role in regulating cell activity and ...
Catherine L. Worth, Annika Kreuchwig, Gunnar Klein...
BIOINFORMATICS
2006
101views more  BIOINFORMATICS 2006»
13 years 7 months ago
A lock-and-key model for protein-protein interactions
Motivation: Protein-protein interaction networks are one of the major post-genomic data sources available to molecular biologists. They provide a comprehensive view of the global ...
Julie L. Morrison, Rainer Breitling, Desmond J. Hi...