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» A graphical model for predicting protein molecular function
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BMCBI
2010
156views more  BMCBI 2010»
13 years 8 months ago
Mathematical model for empirically optimizing large scale production of soluble protein domains
Background: Efficient dissection of large proteins into their structural domains is critical for high throughput proteome analysis. So far, no study has focused on mathematically ...
Eisuke Chikayama, Atsushi Kurotani, Takanori Tanak...
BIOINFORMATICS
2005
169views more  BIOINFORMATICS 2005»
13 years 7 months ago
A statistical model providing comprehensive predictions for the mRNA differential display
s Dirk Tremmel, Maximilian Tropschug N. crassa FKBP22 is part of a protein folding helper complex in the ER [oral presentation] Manuela Heiner A carbamate-cleaving catalytic antibo...
David Meintrup, Ellen Reisinger
BMCBI
2006
108views more  BMCBI 2006»
13 years 8 months ago
SPIDer: Saccharomyces protein-protein interaction database
Background: Since proteins perform their functions by interacting with one another and with other biomolecules, reconstructing a map of the protein-protein interactions of a cell,...
Xiaomei Wu, Lei Zhu, Jie Guo, Cong Fu, Hongjun Zho...
BMCBI
2005
75views more  BMCBI 2005»
13 years 7 months ago
Prediction of a common structural scaffold for proteasome lid, COP9-signalosome and eIF3 complexes
Background: The 'lid' subcomplex of the 26S proteasome and the COP9 signalosome (CSN complex) share a common architecture consisting of six subunits harbouring a so-call...
Hartmut Scheel, Kay Hofmann
ALMOB
2006
155views more  ALMOB 2006»
13 years 8 months ago
A phylogenetic generalized hidden Markov model for predicting alternatively spliced exons
Background: An important challenge in eukaryotic gene prediction is accurate identification of alternatively spliced exons. Functional transcripts can go undetected in gene expres...
Jonathan E. Allen, Steven L. Salzberg