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» A graphical model for protein secondary structure prediction
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RECOMB
2003
Springer
14 years 8 months ago
An integrated probabilistic model for functional prediction of proteins
We develop an integrated probabilistic model to combine protein physical interactions, genetic interactions, highly correlated gene expression network, protein complex data, and d...
Minghua Deng, Ting Chen, Fengzhu Sun
BMCBI
2004
151views more  BMCBI 2004»
13 years 7 months ago
Design, implementation and evaluation of a practical pseudoknot folding algorithm based on thermodynamics
Background: The general problem of RNA secondary structure prediction under the widely used thermodynamic model is known to be NP-complete when the structures considered include a...
Jens Reeder, Robert Giegerich
BMCBI
2006
95views more  BMCBI 2006»
13 years 8 months ago
A quantitative analysis of secondary RNA structure using domination based parameters on trees
Background: It has become increasingly apparent that a comprehensive database of RNA motifs is essential in order to achieve new goals in genomic and proteomic research. Secondary...
Teresa W. Haynes, Debra J. Knisley, Edith Seier, Y...
BMCBI
2008
103views more  BMCBI 2008»
13 years 8 months ago
TOPS++FATCAT: Fast flexible structural alignment using constraints derived from TOPS+ Strings Model
Background: Protein structure analysis and comparison are major challenges in structural bioinformatics. Despite the existence of many tools and algorithms, very few of them have ...
Mallika Veeramalai, Yuzhen Ye, Adam Godzik
WOB
2008
101views Bioinformatics» more  WOB 2008»
13 years 9 months ago
Top-Down Hierarchical Ensembles of Classifiers for Predicting G-Protein-Coupled-Receptor Functions
Abstract. Despite the recent advances in Molecular Biology, the function of a large amount of proteins is still unknown. An approach that can be used in the prediction of a protein...
Eduardo P. Costa, Ana Carolina Lorena, André...