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» A graphical model for protein secondary structure prediction
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BMCBI
2010
122views more  BMCBI 2010»
13 years 8 months ago
Fast and accurate protein substructure searching with simulated annealing and GPUs
Background: Searching a database of protein structures for matches to a query structure, or occurrences of a structural motif, is an important task in structural biology and bioin...
Alex Stivala, Peter J. Stuckey, Anthony Wirth
BIOINFORMATICS
2000
149views more  BIOINFORMATICS 2000»
13 years 7 months ago
MaxSub: an automated measure for the assessment of protein structure prediction quality
Motivation: Evaluating the accuracy of predicted models is critical for assessing structure prediction methods. Because this problem is not trivial, a large number of different as...
Naomi Siew, Arne Elofsson, Leszek Rychlewski, Dani...
PPSC
1997
13 years 9 months ago
Case Studies in Protein Structure Prediction with Real-valued Genetic Algorithms
Accurate and reliable protein structure prediction (PSP) eludes researchers primarily becausethe searchfor theminimumenergyconformeris computationallyintractable. This research di...
Charles E. Kaiser, Laurence D. Merkle, Gary B. Lam...
CSB
2004
IEEE
177views Bioinformatics» more  CSB 2004»
13 years 11 months ago
High-Throughput 3D Structural Homology Detection via NMR Resonance Assignment
One goal of the structural genomics initiative is the identification of new protein folds. Sequence-based structural homology prediction methods are an important means for priorit...
Christopher James Langmead, Bruce Randall Donald
BMCBI
2008
134views more  BMCBI 2008»
13 years 8 months ago
Bioinformatic analyses of mammalian 5'-UTR sequence properties of mRNAs predicts alternative translation initiation sites
Background: Utilization of alternative initiation sites for protein translation directed by non-AUG codons in mammalian mRNAs is observed with increasing frequency. Alternative in...
Jill L. Wegrzyn, Thomas M. Drudge, Faramarz Valafa...