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» A graphical model for protein secondary structure prediction
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BMCBI
2010
132views more  BMCBI 2010»
13 years 9 months ago
New statistical potential for quality assessment of protein models and a survey of energy functions
Background: Scoring functions, such as molecular mechanic forcefields and statistical potentials are fundamentally important tools in protein structure modeling and quality assess...
Dmitry Rykunov, András Fiser
BIBM
2008
IEEE
172views Bioinformatics» more  BIBM 2008»
14 years 3 months ago
Boosting Methods for Protein Fold Recognition: An Empirical Comparison
Protein fold recognition is the prediction of protein’s tertiary structure (Fold) given the protein’s sequence without relying on sequence similarity. Using machine learning t...
Yazhene Krishnaraj, Chandan K. Reddy
BMCBI
2006
160views more  BMCBI 2006»
13 years 9 months ago
Gene prediction in eukaryotes with a generalized hidden Markov model that uses hints from external sources
Background: In order to improve gene prediction, extrinsic evidence on the gene structure can be collected from various sources of information such as genome-genome comparisons an...
Mario Stanke, Oliver Schöffmann, Burkhard Mor...
IJCBDD
2010
127views more  IJCBDD 2010»
13 years 7 months ago
Predicting protein complexes by data integration of different types of interactions
: The explosion of highthroughput interaction data from proteomics studies gives us the opportunity to integrate Protein-Protein Interactions (PPI) from different type of interacti...
Powell Patrick Cheng Tan, Daryanaz Dargahi, Freder...
JCB
2007
136views more  JCB 2007»
13 years 9 months ago
A Structure-Based Flexible Search Method for Motifs in RNA
The discovery of non-coding RNA (ncRNA) motifs and their role in regulating gene expression has recently attracted considerable attention. The goal is to discover these motifs in ...
Isana Veksler-Lublinsky, Michal Ziv-Ukelson, Danny...