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» A graphical model for protein secondary structure prediction
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FLAIRS
2004
13 years 10 months ago
Computing Marginals with Hierarchical Acyclic Hypergraphs
How to compute marginals efficiently is one of major concerned problems in probabilistic reasoning systems. Traditional graphical models do not preserve all conditional independen...
S. K. Michael Wong, Tao Lin
BMCBI
2010
159views more  BMCBI 2010»
13 years 9 months ago
Predicting domain-domain interaction based on domain profiles with feature selection and support vector machines
Background: Protein-protein interaction (PPI) plays essential roles in cellular functions. The cost, time and other limitations associated with the current experimental methods ha...
Alvaro J. González, Li Liao
CANDC
2006
ACM
13 years 9 months ago
Hydrophobic collapse in (in silico) protein folding
A model of hydrophobic collapse, which is treated as the driving force for protein folding, is presented. This model is the superposition of three models commonly used in protein ...
Michal Brylinski, Leszek Konieczny, Irena Roterman
BMCBI
2010
116views more  BMCBI 2010»
13 years 9 months ago
A hybrid approach to protein folding problem integrating constraint programming with local search
Background: The protein folding problem remains one of the most challenging open problems in computational biology. Simplified models in terms of lattice structure and energy func...
Abu Zafer M. Dayem Ullah, Kathleen Steinhöfel
JIB
2007
172views more  JIB 2007»
13 years 9 months ago
The ABC (Analysing Biomolecular Contacts)-database
As protein-protein interactions are one of the basic mechanisms in most cellular processes, it is desirable to understand the molecular details of protein-protein contacts and ult...
Peter Walter, Sam Ansari, Volkhard Helms