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BMCBI
2010
105views more  BMCBI 2010»
13 years 7 months ago
A knowledge-guided strategy for improving the accuracy of scoring functions in binding affinity prediction
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
Tiejun Cheng, Zhihai Liu, Renxiao Wang
BMCBI
2006
148views more  BMCBI 2006»
13 years 7 months ago
Predicting Class II MHC-Peptide binding: a kernel based approach using similarity scores
Background: Modelling the interaction between potentially antigenic peptides and Major Histocompatibility Complex (MHC) molecules is a key step in identifying potential T-cell epi...
Jesper Salomon, Darren R. Flower
IJCNN
2006
IEEE
14 years 1 months ago
Non-Relevance Feedback Document Retrieval based on One Class SVM and SVDD
— This paper reports a new document retrieval method using non-relevant documents. Especially, this paper reports a comparison of retrieval efficiency between One Class Support ...
Takashi Onoda, Hiroshi Murata, Seiji Yamada
BMCBI
2008
202views more  BMCBI 2008»
13 years 7 months ago
Network motif-based identification of transcription factor-target gene relationships by integrating multi-source biological data
Background: Integrating data from multiple global assays and curated databases is essential to understand the spatiotemporal interactions within cells. Different experiments measu...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...
WWW
2009
ACM
14 years 8 months ago
RuralCafe: web search in the rural developing world
The majority of people in rural developing regions do not have access to the World Wide Web. Traditional network connectivity technologies have proven to be prohibitively expensiv...
Jay Chen, Lakshminarayanan Subramanian, Jinyang Li