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» A measure of similarity between graph vertices
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BMCBI
2010
178views more  BMCBI 2010»
13 years 7 months ago
An improved method for scoring protein-protein interactions using semantic similarity within the Gene Ontology
Background: Semantic similarity measures are useful to assess the physiological relevance of protein-protein interactions (PPIs). They quantify similarity between proteins based o...
Shobhit Jain, Gary D. Bader
UAI
2003
13 years 8 months ago
Learning Generative Models of Similarity Matrices
Recently, spectral clustering (a.k.a. normalized graph cut) techniques have become popular for their potential ability at finding irregularlyshaped clusters in data. The input to...
Rómer Rosales, Brendan J. Frey
BIBE
2006
IEEE
154views Bioinformatics» more  BIBE 2006»
14 years 1 months ago
Determining Molecular Similarity for Drug Discovery using the Wavelet Riemannian Metric
Discerning the similarity between two molecules is a challenging problem in drug discovery as well as in molecular biology. The importance of this problem is due to the fact that ...
Elinor Velasquez, Emmanuel R. Yera, Rahul Singh
LPAR
2004
Springer
14 years 23 days ago
Entanglement - A Measure for the Complexity of Directed Graphs with Applications to Logic and Games
We propose a new parameter for the complexity of finite directed graphs which measures to what extent the cycles of the graph are intertwined. This measure, called entanglement, i...
Dietmar Berwanger, Erich Grädel
BMCBI
2010
82views more  BMCBI 2010»
13 years 7 months ago
Predicting the network of substrate-enzyme-product triads by combining compound similarity and functional domain composition
Background: Metabolic pathway is a highly regulated network consisting of many metabolic reactions involving substrates, enzymes, and products, where substrates can be transformed...
Lei Chen, Kai-Yan Feng, Yu-Dong Cai, Kuo-Chen Chou...