Background: Semantic similarity measures are useful to assess the physiological relevance of protein-protein interactions (PPIs). They quantify similarity between proteins based o...
Recently, spectral clustering (a.k.a. normalized graph cut) techniques have become popular for their potential ability at finding irregularlyshaped clusters in data. The input to...
Discerning the similarity between two molecules is a challenging problem in drug discovery as well as in molecular biology. The importance of this problem is due to the fact that ...
We propose a new parameter for the complexity of finite directed graphs which measures to what extent the cycles of the graph are intertwined. This measure, called entanglement, i...
Background: Metabolic pathway is a highly regulated network consisting of many metabolic reactions involving substrates, enzymes, and products, where substrates can be transformed...
Lei Chen, Kai-Yan Feng, Yu-Dong Cai, Kuo-Chen Chou...