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BIOINFORMATICS
2010
127views more  BIOINFORMATICS 2010»
13 years 7 months ago
Analyzing taxonomic classification using extensible Markov models
Motivation: As next generation sequencing is rapidly adding new genomes, their correct placement in the taxonomy needs verification. However, the current methods for confirming cl...
Rao M. Kotamarti, Michael Hahsler, Douglas Raiford...
BMCBI
2010
93views more  BMCBI 2010»
13 years 7 months ago
Hybridization thermodynamics of NimbleGen Microarrays
Background: While microarrays are the predominant method for gene expression profiling, probe signal variation is still an area of active research. Probe signal is sequence depend...
Ulrike Mückstein, Germán G. Leparc, Al...
BMCBI
2008
103views more  BMCBI 2008»
13 years 7 months ago
TOPS++FATCAT: Fast flexible structural alignment using constraints derived from TOPS+ Strings Model
Background: Protein structure analysis and comparison are major challenges in structural bioinformatics. Despite the existence of many tools and algorithms, very few of them have ...
Mallika Veeramalai, Yuzhen Ye, Adam Godzik
NAR
2000
128views more  NAR 2000»
13 years 6 months ago
The IMB Jena Image Library of Biological Macromolecules
The IMB Jena Image Library of Biological Macromolecules (http://www.imb-jena.de/IMAGE.html ) is aimed at a better dissemination of information on three-dimensional biopolymer stru...
Jan Reichert, Andreas Jabs, Peter Slickers, Jü...
BMCBI
2005
125views more  BMCBI 2005»
13 years 6 months ago
Multiple sequence alignments of partially coding nucleic acid sequences
Background: High quality sequence alignments of RNA and DNA sequences are an important prerequisite for the comparative analysis of genomic sequence data. Nucleic acid sequences, ...
Roman R. Stocsits, Ivo L. Hofacker, Claudia Fried,...