Background: Leishmaniasis is a virulent parasitic infection that causes a worldwide disease burden. Most treatments have toxic side-effects and efficacy has decreased due to the e...
Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...
Angela del Pozo, Florencio Pazos, Alfonso Valencia
Background: Serial analysis of gene expression (SAGE) is used to obtain quantitative snapshots of the transcriptome. These profiles are count-based and are assumed to follow a Bin...
Background: Automated protein function prediction methods are needed to keep pace with high-throughput sequencing. With the existence of many programs and databases for inferring ...
Background: Construction and interpretation of phylogenetic trees has been a major research topic for understanding the evolution of genes. Increases in sequence data and complexi...