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JBI
2002
13 years 7 months ago
Revising regulatory networks: from expression data to linear causal models
Discovering the complex regulatory networks that govern mRNA expression is an important but difficult problem. Many current approaches use only expression data from microarrays to...
Stephen D. Bay, Jeff Shrager, Andrew Pohorille, Pa...
ALMOB
2007
111views more  ALMOB 2007»
13 years 7 months ago
Transcriptional regulatory network discovery via multiple method integration: application to e. coli K12
Motivation: Transcriptional regulatory network (TRN) discovery from one method (e.g. microarray analysis, gene ontology, phylogenic similarity) does not seem feasible due to lack ...
Jingjun Sun, Kagan Tuncay, Alaa Abi Haidar, Lisa E...
VLDB
2004
ACM
143views Database» more  VLDB 2004»
14 years 24 days ago
GPX: Interactive Mining of Gene Expression Data
Discovering co-expressed genes and coherent expression patterns in gene expression data is an important data analysis task in bioinformatics research and biomedical applications. ...
Daxin Jiang, Jian Pei, Aidong Zhang
SDM
2004
SIAM
162views Data Mining» more  SDM 2004»
13 years 8 months ago
Subspace Clustering of High Dimensional Data
Clustering suffers from the curse of dimensionality, and similarity functions that use all input features with equal relevance may not be effective. We introduce an algorithm that...
Carlotta Domeniconi, Dimitris Papadopoulos, Dimitr...
BMCBI
2008
129views more  BMCBI 2008»
13 years 7 months ago
Motif-directed network component analysis for regulatory network inference
Background: Network Component Analysis (NCA) has shown its effectiveness in discovering regulators and inferring transcription factor activities (TFAs) when both microarray data a...
Chen Wang, Jianhua Xuan, Li Chen, Po Zhao, Yue Wan...