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» A multiple layer model to compare RNA secondary structures
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BMCBI
2006
114views more  BMCBI 2006»
13 years 7 months ago
Impact of RNA structure on the prediction of donor and acceptor splice sites
Background: gene identification in genomic DNA sequences by computational methods has become an important task in bioinformatics and computational gene prediction tools are now es...
Sayed-Amir Marashi, Changiz Eslahchi, Hamid Pezesh...
BMCBI
2004
126views more  BMCBI 2004»
13 years 7 months ago
A probabilistic model for the evolution of RNA structure
Background: For the purposes of finding and aligning noncoding RNA gene- and cis-regulatory elements in multiple-genome datasets, it is useful to be able to derive multi-sequence ...
Ian Holmes
BIB
2008
86views more  BIB 2008»
13 years 7 months ago
Recent developments in the MAFFT multiple sequence alignment program
The accuracy and scalability of multiple sequence alignment (MSA) of DNAs and proteins have long been and are still important issues in bioinformatics. To rapidly construct a reas...
Kazutaka Katoh, Hiroyuki Toh
BMCBI
2010
152views more  BMCBI 2010»
13 years 7 months ago
Comparative study of three commonly used continuous deterministic methods for modeling gene regulation networks
Background: A gene-regulatory network (GRN) refers to DNA segments that interact through their RNA and protein products and thereby govern the rates at which genes are transcribed...
Martin T. Swain, Johannes J. Mandel, Werner Dubitz...
BMCBI
2010
93views more  BMCBI 2010»
13 years 7 months ago
Hybridization thermodynamics of NimbleGen Microarrays
Background: While microarrays are the predominant method for gene expression profiling, probe signal variation is still an area of active research. Probe signal is sequence depend...
Ulrike Mückstein, Germán G. Leparc, Al...