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BMCBI
2008
102views more  BMCBI 2008»
13 years 7 months ago
Fast splice site detection using information content and feature reduction
Background: Accurate identification of splice sites in DNA sequences plays a key role in the prediction of gene structure in eukaryotes. Already many computational methods have be...
A. K. M. A. Baten, Saman K. Halgamuge, Bill C. H. ...
BMCBI
2005
92views more  BMCBI 2005»
13 years 7 months ago
Predicting functional sites with an automated algorithm suitable for heterogeneous datasets
Background: In a previous report (La et al., Proteins, 2005), we have demonstrated that the identification of phylogenetic motifs, protein sequence fragments conserving the overal...
David La, Dennis R. Livesay
GCCB
2006
13 years 11 months ago
Accelerated microRNA-Precursor Detection Using the Smith-Waterman Algorithm on FPGAs
During the last few years more and more functionalities of RNA have been discovered that were previously thought of being carried out by proteins alone. One of the most striking di...
Patrick May, Gunnar W. Klau, Markus Bauer, Thomas ...
IPPS
2003
IEEE
14 years 21 days ago
A Fast Algorithm for the Exhaustive Analysis of 12-Nucleotide-Long DNA Sequences. Applications to Human Genomics
We have developed a new algorithm that allows the exhaustive determination of words of up to 12 nucleotides in DNA sequences. It is fast enough as to be used at a genomic scale ru...
Vicente Arnau, Ignacio Marín
BMCBI
2010
136views more  BMCBI 2010»
13 years 7 months ago
Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfa
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...