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JCB
2002
116views more  JCB 2002»
13 years 7 months ago
A Novel Approach to Remote Homology Detection: Jumping Alignments
We describe a new algorithm for protein classi cation and the detection of remote homologs. The rationale is to exploit both vertical and horizontal information of a multiple alig...
Rainer Spang, Marc Rehmsmeier, Jens Stoye
BMCBI
2010
118views more  BMCBI 2010»
13 years 7 months ago
Bacillus anthracis genome organization in light of whole transcriptome sequencing
Emerging knowledge of whole prokaryotic transcriptomes could validate a number of theoretical concepts introduced in the early days of genomics. What are the rules connecting gene...
Jeffrey Martin, Wenhan Zhu, Karla D. Passalacqua, ...
BIOINFORMATICS
2005
140views more  BIOINFORMATICS 2005»
13 years 7 months ago
Profile-based direct kernels for remote homology detection and fold recognition
Motivation: Remote homology detection between protein sequences is a central problem in computational biology. Supervised learning algorithms based on support vector machines are ...
Huzefa Rangwala, George Karypis
ISMB
1994
13 years 8 months ago
An Improved System for Exon Recognition and Gene Modeling in Human DNA Sequence
A new version of the GRAIL system (Uberbacher and Mural, 1991; Mural et al., 1992; Uberbacher et al., 1993), called GRAILII, has recently been developed (Xu et al., 1994). GRAILII...
Yin Xu, J. Ralph Einstein, Richard J. Mural, Manes...
BIRD
2007
Springer
117views Bioinformatics» more  BIRD 2007»
14 years 1 months ago
Enhancing Protein Disorder Detection by Refined Secondary Structure Prediction
More and more proteins have been observed to display functions through intrinsic disorder. Such structurally flexible regions are shown to play important roles in biological proces...
Chung-Tsai Su, Tong-Ming Hsu, Chien-Yu Chen, Yu-Ye...