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» A new approach to fragment assembly in DNA sequencing
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BMCBI
2011
12 years 11 months ago
LAVA: An Open-Source Approach To Designing LAMP (Loop-Mediated Isothermal Amplification) DNA Signatures
Background: We developed an extendable open-source Loop-mediated isothermal AMPlification (LAMP) signature design program called LAVA (LAMP Assay Versatile Analysis). LAVA was cre...
Clinton Torres, Elizabeth A. Vitalis, Brian R. Bak...
BMCBI
2004
96views more  BMCBI 2004»
13 years 7 months ago
Identification of regions in multiple sequence alignments thermodynamically suitable for targeting by consensus oligonucleotides
Background: Computer programs for the generation of multiple sequence alignments such as "Clustal W" allow detection of regions that are most conserved among many sequen...
Olga V. Matveeva, Brian T. Foley, Vladimir A. Nemt...
BMCBI
2010
144views more  BMCBI 2010»
13 years 7 months ago
Graph-based clustering and characterization of repetitive sequences in next-generation sequencing data
Background: The investigation of plant genome structure and evolution requires comprehensive characterization of repetitive sequences that make up the majority of higher plant nuc...
Petr Novák, Pavel Neumann, Jirí Maca...
BMCBI
2004
167views more  BMCBI 2004»
13 years 7 months ago
Feature selection for splice site prediction: A new method using EDA-based feature ranking
Background: The identification of relevant biological features in large and complex datasets is an important step towards gaining insight in the processes underlying the data. Oth...
Yvan Saeys, Sven Degroeve, Dirk Aeyels, Pierre Rou...
RECOMB
2010
Springer
14 years 2 months ago
A Novel Abundance-Based Algorithm for Binning Metagenomic Sequences Using l-Tuples
Abstract. Metagenomics is the study of microbial communities sampled directly from their natural environment, without prior culturing. Among the computational tools recently develo...
Yu-Wei Wu, Yuzhen Ye