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» A new approach to fragment assembly in DNA sequencing
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RECOMB
2000
Springer
13 years 11 months ago
Contig selection in physical mapping
In physical mapping, one orders a set of genetic landmarks or a library of cloned fragments of DNA according to their position in the genome. Our approach to physical mapping divi...
Steffen Heber, Jens Stoye, Jörg D. Hoheisel, ...
BMCBI
2010
152views more  BMCBI 2010»
13 years 7 months ago
A high-throughput de novo sequencing approach for shotgun proteomics using high-resolution tandem mass spectrometry
Background: High-resolution tandem mass spectra can now be readily acquired with hybrid instruments, such as LTQ-Orbitrap and LTQ-FT, in high-throughput shotgun proteomics workflo...
Chongle Pan, Byung-Hoon Park, William H. McDonald,...
DNA
2007
Springer
14 years 1 months ago
Staged Self-assembly: Nanomanufacture of Arbitrary Shapes with O (1) Glues
We introduce staged self-assembly of Wang tiles, where tiles can be added dynamically in sequence and where intermediate constructions can be stored for later mixing. This model a...
Erik D. Demaine, Martin L. Demaine, Sándor ...
BMCBI
2005
94views more  BMCBI 2005»
13 years 7 months ago
A method for finding single-nucleotide polymorphisms with allele frequencies in sequences of deep coverage
Background: The allele frequencies of single-nucleotide polymorphisms (SNPs) are needed to select an optimal subset of common SNPs for use in association studies. Sequence-based m...
Jianmin Wang, Xiaoqiu Huang
BMCBI
2011
12 years 11 months ago
A Novel And Well-Defined Benchmarking Method For Second Generation Read Mapping
Background: Second generation sequencing technologies yield DNA sequence data at ultra high-throughput. Common to most biological applications is a mapping of the reads to an almo...
Manuel Holtgrewe, Anne-Katrin Emde, David Weese, K...