Background: ChIP-Seq, which combines chromatin immunoprecipitation (ChIP) with high-throughput massively parallel sequencing, is increasingly being used for identification of prot...
Congmao Wang, Jie Xu, Dasheng Zhang, Zoe A. Wilson...
Background: In expressed sequence tag (EST) sequencing, we are often interested in how many genes we can capture in an EST sample of a targeted size. This information provides ins...
Ji-Ping Z. Wang, Bruce G. Lindsay 0002, Liying Cui...
— Automated DNA sequencing produces a large amount of raw DNA sequence data that then needs to be classified, organized, and annotation. One major application is the comparison o...
Guillermo Tonsmann, David D. Pollock, Wanjun Gu, T...
The Smith-Waterman algorithm for local sequence alignment is one of the most important techniques in computational molecular biology. This ingenious dynamic programming approach w...
Optical mapping is an integrated system for the analysis of single DNA molecules. It constructs restriction maps (noted as “optical map”) from individual DNA molecules present...
Haifeng Li, Anton Valouev, David C. Schwartz, Mich...