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    BMCBI
    2004
    146views more  BMCBI 2004»
    Defining transcriptional networks through integrative modeling of mRNA expression and transcription factor binding data
    13 years 7 months ago
    Defining transcriptional networks through integrative modeling of mRNA expression and transcription factor binding data
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    Background: Functional genomics studies are yielding information about regulatory processes in the cell at an unprecedented scale. In the yeast S. cerevisiae, DNA microarrays have...
    Feng Gao, Barrett C. Foat, Harmen J. Bussemaker
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    BMCBI
    2005
    107views more  BMCBI 2005»
    Identifying differential expression in multiple SAGE libraries: an overdispersed log-linear model approach
    13 years 7 months ago
    Identifying differential expression in multiple SAGE libraries: an overdispersed log-linear model approach
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    Background: In testing for differential gene expression involving multiple serial analysis of gene expression (SAGE) libraries, it is critical to account for both between and with...
    Jun Lu, John K. Tomfohr, Thomas B. Kepler
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    BMCBI
    2011
    188views Artificial Intelligence» more  BMCBI 2011»
    Investigating the effect of paralogs on microarray gene-set analysis
    13 years 2 months ago
    Investigating the effect of paralogs on microarray gene-set analysis
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    Background: In order to interpret the results obtained from a microarray experiment, researchers often shift focus from analysis of individual differentially expressed genes to an...
    Andre J. Faure, Cathal Seoighe, Nicola J. Mulder
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    RECOMB
    2000
    Springer
    131views Computational Biology» more  RECOMB 2000»
    Using Bayesian networks to analyze expression data
    13 years 11 months ago
    Using Bayesian networks to analyze expression data
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    DNA hybridization arrays simultaneously measure the expression level for thousands of genes. These measurements provide a "snapshot" of transcription levels within the c...
    Nir Friedman, Michal Linial, Iftach Nachman, Dana ...
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    BMCBI
    2008
    124views more  BMCBI 2008»
    A probe-treatment-reference (PTR) model for the analysis of oligonucleotide expression microarrays
    13 years 7 months ago
    A probe-treatment-reference (PTR) model for the analysis of oligonucleotide expression microarrays
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    Background: Microarray pre-processing usually consists of normalization and summarization. Normalization aims to remove non-biological variations across different arrays. The norm...
    Huanying Ge, Chao Cheng, Lei M. Li
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