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NCA
2007
IEEE
13 years 7 months ago
A data reduction approach for resolving the imbalanced data issue in functional genomics
Learning from imbalanced data occurs frequently in many machine learning applications. One positive example to thousands of negative instances is common in scientific applications...
Kihoon Yoon, Stephen Kwek
CSB
2003
IEEE
121views Bioinformatics» more  CSB 2003»
14 years 22 days ago
Epitope Prediction Algorithms for Peptide based Vaccine Design
Peptide-based vaccines, in which small peptides derived from target proteins (epitopes) are used to provoke an immune reaction, have attracted considerable attention recently as a...
Liliana Florea, Bjarni V. Halldórsson, Oliv...
JCB
2007
106views more  JCB 2007»
13 years 7 months ago
Clustered Sequence Representation for Fast Homology Search
We present a novel approach to managing redundancy in sequence databanks such as GenBank. We store clusters of near-identical sequences as a representative union-sequence and a se...
Michael Cameron, Yaniv Bernstein, Hugh E. Williams
BMCBI
2011
13 years 2 months ago
Support vector machines-based identification of alternative splicing in Arabidopsis thaliana from whole-genome tiling arrays
Background: Alternative splicing (AS) is a process which generates several distinct mRNA isoforms from the same gene by splicing different portions out of the precursor transcript...
Johannes Eichner, Georg Zeller, Sascha Laubinger, ...
BMCBI
2010
117views more  BMCBI 2010»
13 years 7 months ago
New decoding algorithms for Hidden Markov Models using distance measures on labellings
Background: Existing hidden Markov model decoding algorithms do not focus on approximately identifying the sequence feature boundaries. Results: We give a set of algorithms to com...
Daniel G. Brown 0001, Jakub Truszkowski