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» A polyhedral approach to RNA sequence structure alignment
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BMCBI
2011
13 years 3 months ago
Multithreaded comparative RNA secondary structure prediction using stochastic context-free grammars
Background: The prediction of the structure of large RNAs remains a particular challenge in bioinformatics, due to the computational complexity and low levels of accuracy of state...
Zsuzsanna Sukosd, Bjarne Knudsen, Morten Vaerum, J...
CONSTRAINTS
2008
95views more  CONSTRAINTS 2008»
13 years 8 months ago
Efficient Sequence Alignment with Side-Constraints by Cluster Tree Elimination
Aligning DNA and protein sequences is a core technique in molecular biology. Often, it is desirable to include partial prior knowledge and conditions in an alignment. Going beyond...
Sebastian Will, Anke Busch, Rolf Backofen
CSB
2004
IEEE
142views Bioinformatics» more  CSB 2004»
14 years 14 days ago
FastR: Fast Database Search Tool for Non-Coding RNA
The discovery of novel non-coding RNAs has been among the most exciting recent developments in Biology. Yet, many more remain undiscovered. It has been hypothesized that there is ...
Vineet Bafna, Shaojie Zhang
BMCBI
2004
133views more  BMCBI 2004»
13 years 8 months ago
Evaluation of several lightweight stochastic context-free grammars for RNA secondary structure prediction
Background: RNA secondary structure prediction methods based on probabilistic modeling can be developed using stochastic context-free grammars (SCFGs). Such methods can readily co...
Robin D. Dowell, Sean R. Eddy
BIOCOMP
2006
13 years 10 months ago
An Approach to Selecting Putative RNA Motifs Using MDL Principle
The history of molecular biology is punctuated by a series of discoveries demonstrating the surprising breadth of biological roles of ribonucleic acid (RNA). An ensemble of evoluti...
Mohammad Anwar, Marcel Turcotte