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» A polyhedral approach to RNA sequence structure alignment
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BMCBI
2004
177views more  BMCBI 2004»
13 years 8 months ago
Gapped alignment of protein sequence motifs through Monte Carlo optimization of a hidden Markov model
Background: Certain protein families are highly conserved across distantly related organisms and belong to large and functionally diverse superfamilies. The patterns of conservati...
Andrew F. Neuwald, Jun S. Liu
LSSC
2007
Springer
14 years 2 months ago
An Ant-Based Model for Multiple Sequence Alignment
Abstract. Multiple sequence alignment is a key process in today’s biology, and finding a relevant alignment of several sequences is much more challenging than just optimizing so...
Frédéric Guinand, Yoann Pigné
BMCBI
2004
151views more  BMCBI 2004»
13 years 8 months ago
Design, implementation and evaluation of a practical pseudoknot folding algorithm based on thermodynamics
Background: The general problem of RNA secondary structure prediction under the widely used thermodynamic model is known to be NP-complete when the structures considered include a...
Jens Reeder, Robert Giegerich
COMPLIFE
2005
Springer
14 years 2 months ago
Protein Annotation by Secondary Structure Based Alignments (PASSTA)
Abstract. Most software tools in homology recognition on proteins answer only a few specific questions, often leaving not much room for the interpretation of the results. We devel...
Constantin Bannert, Jens Stoye
RECOMB
2005
Springer
14 years 9 months ago
RNA-RNA Interaction Prediction and Antisense RNA Target Search
Abstract. Recent studies demonstrating the existence of special non-coding "antisense" RNAs used in post-transcriptional gene regulation have received considerable attent...
Can Alkan, Emre Karakoç, Joseph H. Nadeau, ...