Sciweavers

154 search results - page 4 / 31
» A polyhedral approach to sequence alignment problems
Sort
View
CPM
1993
Springer
154views Combinatorics» more  CPM 1993»
14 years 1 months ago
On Suboptimal Alignments of Biological Sequences
It is widely accepted that the optimal alignment between a pair of proteins or nucleic acid sequences that minimizes the edit distance may not necessarily re ect the correct biolog...
Dalit Naor, Douglas L. Brutlag
BMEI
2008
IEEE
14 years 4 months ago
A New Approach for Tree Alignment Based on Local Re-Optimization
Multiple sequence alignment is the most fundamental task in bioinformatics and computational biology. In this paper, we present a new algorithm to conduct multiple sequences align...
Feng Yue, Jijun Tang
GCB
2006
Springer
140views Biometrics» more  GCB 2006»
14 years 1 months ago
PALMA: Perfect Alignments using Large Margin Algorithms
: Despite many years of research on how to properly align sequences in the presence of sequencing errors, alternative splicing and micro-exons, the correct alignment of mRNA sequen...
Gunnar Rätsch, Bettina Hepp, Uta Schulze, Che...
IDA
2007
Springer
14 years 4 months ago
Learning to Align: A Statistical Approach
We present a new machine learning approach to the inverse parametric sequence alignment problem: given as training examples a set of correct pairwise global alignments, find the p...
Elisa Ricci, Tijl De Bie, Nello Cristianini
BMCBI
2005
122views more  BMCBI 2005»
13 years 9 months ago
Bayesian coestimation of phylogeny and sequence alignment
Background: Two central problems in computational biology are the determination of the alignment and phylogeny of a set of biological sequences. The traditional approach to this p...
Gerton Lunter, István Miklós, Alexei...