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BMCBI
2010
98views more  BMCBI 2010»
13 years 8 months ago
Learning to predict expression efficacy of vectors in recombinant protein production
Background: Recombinant protein production is a useful biotechnology to produce a large quantity of highly soluble proteins. Currently, the most widely used production system is t...
Wen-Ching Chan, Po-Huang Liang, Yan-Ping Shih, Uen...
BIOSYSTEMS
2007
109views more  BIOSYSTEMS 2007»
13 years 8 months ago
Protein folding and the robustness of cells
The intricate intracellular infrastructure of all known life forms is based on proteins. The folded shape of a protein determines both the protein’s function and the set of mole...
G. J. Shawn Tan, Ferran D. Revilla, Klaus-Peter Za...
BMCBI
2010
152views more  BMCBI 2010»
13 years 8 months ago
Comparative study of three commonly used continuous deterministic methods for modeling gene regulation networks
Background: A gene-regulatory network (GRN) refers to DNA segments that interact through their RNA and protein products and thereby govern the rates at which genes are transcribed...
Martin T. Swain, Johannes J. Mandel, Werner Dubitz...
BIOCOMP
2006
13 years 10 months ago
Reverse Engineering Approach in Molecular Evolution: Simulation and Case Study with Enzyme Proteins
- We developed a method of reverse engineering to compare the behaviour the enzyme proteins with the existing standard concepts. Our work is based on the strong assumption from the...
Sukanya Manna, Cheng-Yuan Liou
CANDC
2004
ACM
13 years 8 months ago
Identification of related gene/protein names based on an HMM of name variations
Gene and protein names follow few, if any, true naming conventions and are subject to great variation in different occurrences of the same name. This gives rise to two important p...
Lana Yeganova, Lawrence H. Smith, W. John Wilbur