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BMCBI
2010
83views more  BMCBI 2010»
13 years 8 months ago
An effective approach for generating a three-Cys2His2 zinc-finger-DNA complex model by docking
Background: Determination of protein-DNA complex structures with both NMR and X-ray crystallography remains challenging in many cases. High Ambiguity-Driven DOCKing (HADDOCK) is a...
Chun-Chi Chou, M. Rajasekaran, Chinpan Chen
BIBE
2004
IEEE
149views Bioinformatics» more  BIBE 2004»
14 years 14 days ago
Interactive 3D Protein Structure Visualization Using Virtual Reality
Large-scale biomedical data sets of macromolecular structures such as DNA and proteins describe highly complex biomolecular entities which often consist of thousands of atoms and ...
Elke Moritz, Jörg Meyer
BMCBI
2006
103views more  BMCBI 2006»
13 years 8 months ago
Domain-based small molecule binding site annotation
Background: Accurate small molecule binding site information for a protein can facilitate studies in drug docking, drug discovery and function prediction, but small molecule bindi...
Kevin A. Snyder, Howard J. Feldman, Michel Dumonti...
BMCBI
2007
216views more  BMCBI 2007»
13 years 8 months ago
A replica exchange Monte Carlo algorithm for protein folding in the HP model
Background: The ab initio protein folding problem consists of predicting protein tertiary structure from a given amino acid sequence by minimizing an energy function; it is one of...
Chris Thachuk, Alena Shmygelska, Holger H. Hoos
CIBCB
2005
IEEE
14 years 2 months ago
Intrinsic Disorder and Protein modifications: Building an SVM Predictor for Methylation
Abstract-Post-translational protein modifications play an important role in many protein pathways and interactions. It has been hypothesized that modifications to proteins occur in...
Kenneth Daily, Predrag Radivojac, A. Keith Dunker